Toxicokinetics of Metformin During Hemodialysis
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Toxicokinetics of Metformin During Hemodialysis
To the Editor: Metformin-associated lactic acidosis (MALA) following metformin overdose or reduced metformin clearance in the setting of acute kidney injury is associated with high mortality. For most severe cases, current guidelines recommend hemodialysis (HD) to correct acidosis and associated electrolyte abnormalities, although its effect on metformin removal is considered uncertain. We repo...
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ژورنال
عنوان ژورنال: Kidney International Reports
سال: 2017
ISSN: 2468-0249
DOI: 10.1016/j.ekir.2017.02.017